scientists have traced genetic risk associated with migraine attacks, which might make it possible for the novel therapeutics to prevent migraine attacks.

Researchers looked at the genetic data of more than 50,000 people.

The team found that patients with a particular DNA variant on Chromosome 8 between two genes - PGCP and MTDH/AEG-1 - have a significantly greater risk for developing migraine.

The team also discovered a potential explanation for this link. It appears that the associated DNA variant regulates levels of glutamate - a chemical, known as a neurotransmitter, which transports messages between nerve cells in the brain.

The results suggest that an accumulation of glutamate in nerve cell junctions (synapses) in the brain may play a key role in the initiation of migraine attacks.